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FcgammaR expression on macrophages is related to severity and chronicity of synovial inflammation and cartilage destruction during experimental immune-complex-mediated arthritis (ICA)

INTRODUCTION: Fcγ receptors (FcγRs) present on cells of the haematopoietic lineage communicate with IgG-containing immune complexes that are abundant in the synovial tissue of patients with rheumatoid arthritis (RA). In mice, three classes of FcγR (RI, RII, and RIII) have been described. Binding of...

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Autors principals: Blom, Arjen B, van Lent, Peter L, van Vuuren, Hanneke, Holthuysen, Astrid E, Jacobs, Cor, van de Putte, Leo B, van de Winkel, Jan G, van den Berg, Wim B
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17821/
https://ncbi.nlm.nih.gov/pubmed/11056679
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