Local removal of phagocytic synovial lining cells by clodronate-liposomes decreases cartilage destruction during collagen type II arthritis

OBJECTIVE—To investigate whether local removal of phagocytic synovial lining cells (SLCs) from the knee joint before onset of collagen type II arthritis has an effect on development of cartilage destruction.
METHODS—Phagocytic SLCs were selectively depleted by a single injection of clodronate laden...

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Detalhes bibliográficos
Main Authors: Van Lent, P L E M, Holthuysen, A, Van Rooijen, N, De Putte, L B A V., Den Berg, W B V.
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Extended Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752671/
https://ncbi.nlm.nih.gov/pubmed/9797567
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