Local removal of phagocytic synovial lining cells by clodronate-liposomes decreases cartilage destruction during collagen type II arthritis

OBJECTIVE—To investigate whether local removal of phagocytic synovial lining cells (SLCs) from the knee joint before onset of collagen type II arthritis has an effect on development of cartilage destruction.
METHODS—Phagocytic SLCs were selectively depleted by a single injection of clodronate laden...

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Autors principals: Van Lent, P L E M, Holthuysen, A, Van Rooijen, N, De Putte, L B A V., Den Berg, W B V.
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Extended Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752671/
https://ncbi.nlm.nih.gov/pubmed/9797567
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