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Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4(+) naïve T cells

Interleukin-7 (IL-7) is produced by bone marrow and lymphoid stromal cells and is involved in the synthesis, survival and homeostasis of T cells. These attributes are the basis for current strategies to utilize IL-7 as an immune modulator for several clinical conditions to replenish depleted T-cell...

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Bibliografiske detaljer
Main Authors: Managlia, Elizabeth Z, Landay, Alan, Al-Harthi, Lena
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782087/
https://ncbi.nlm.nih.gov/pubmed/15720434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.02089.x
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