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Dimerization in protein kinase signaling

The closely related mitogen-activated protein kinases ERK1 and ERK2 have now been shown to have opposing roles in Ras-mediated cell proliferation. I propose that dimerization of these highly related protein kinases could underlie these surprising observations and that this could be a common paradigm...

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Detalhes bibliográficos
Autor principal: Pelech, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781521/
https://ncbi.nlm.nih.gov/pubmed/16879720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol45
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