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Dimerization in protein kinase signaling
The closely related mitogen-activated protein kinases ERK1 and ERK2 have now been shown to have opposing roles in Ras-mediated cell proliferation. I propose that dimerization of these highly related protein kinases could underlie these surprising observations and that this could be a common paradigm...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1781521/ https://ncbi.nlm.nih.gov/pubmed/16879720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol45 |
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