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Promoter Polymorphisms in the Plasma Glutathione Peroxidase (GPx-3) Gene: A Novel Risk Factor for Arterial Ischemic Stroke among Young Adults and Children

BACKGROUND AND PURPOSE: Plasma glutathione peroxidase (GPx-3) deficiency increases extracellular oxidant stress, decreases bioavailable nitric oxide, and promotes platelet activation. The aim of this study is to identify polymorphisms in the GPx-3 gene, examine their relationship to arterial ischemi...

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Detalhes bibliográficos
Main Authors: Voetsch, Barbara, Jin, Richard C., Bierl, Charlene, Benke, Kelly S., Kenet, Gili, Simioni, Paolo, Ottaviano, Filomena, Damasceno, Benito P., Annichino-Bizacchi, Joyce M., Handy, Diane E., Loscalzo, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781064/
https://ncbi.nlm.nih.gov/pubmed/17122425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.STR.0000252027.53766.2b
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