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Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction
Homocyst(e)ine (Hcy) inhibits the expression of the antioxidant enzyme cellular glutathione peroxidase (GPx-1) in vitro and in vivo, which can lead to an increase in reactive oxygen species that inactivate NO and promote endothelial dysfunction. In this study, we tested the hypothesis that overexpre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60083/ https://ncbi.nlm.nih.gov/pubmed/11606774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231428998 |
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