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Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction

AIMS: PTEN is a novel tumour suppressor which exhibits tyrosine phosphatase activity as well as homology to the cytoskeletal proteins tensin and auxilin. Mutations of PTEN have been described in several human cancers and associated with their invasiveness and metastatic properties. Although not mali...

詳細記述

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書誌詳細
出版年:Arthritis Res
主要な著者: Pap, Thomas, Franz, Juliane K, Hummel, Klaus M, Jeisy, Elvira, Gay, Renate, Gay, Steffen
フォーマット: Artigo
言語:Inglês
出版事項: BMC 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11219390/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar69
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