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Functional Characterization of a Naturally Occurring Cx50 Truncation

PURPOSE. Lens connexins undergo proteolytic cleavage of their C termini during fiber maturation. Although the functional significance of this is unknown, cleavage has been correlated with changes in channel-gating properties. This study evaluates the functional consequences of this endogenous trunca...

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Main Authors: DeRosa, Adam M., Mui, Rickie, Srinivas, Miduturu, White, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780262/
https://ncbi.nlm.nih.gov/pubmed/17003442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1582
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