Aberrant Collagenase Expression in Chronic Idiopathic Myelofibrosis Is Related to the Stage of Disease but Not to the JAK2 Mutation Status

Bone marrow fibrosis in chronic idiopathic myelofibrosis (cIMF) most likely represents an imbalance between synthesis and turnover of collagen fibers. Because the JAK-STAT signaling pathway is involved in the regulation of genes encoding matrix metalloproteinases (MMPs), we examined the expression o...

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Autori principali: Bock, Oliver, Neuse, Johanne, Hussein, Kais, Brakensiek, Kai, Buesche, Guntram, Buhr, Thomas, Wiese, Birgitt, Kreipe, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2006
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780160/
https://ncbi.nlm.nih.gov/pubmed/16877349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060110
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