Aberrant Collagenase Expression in Chronic Idiopathic Myelofibrosis Is Related to the Stage of Disease but Not to the JAK2 Mutation Status

Bone marrow fibrosis in chronic idiopathic myelofibrosis (cIMF) most likely represents an imbalance between synthesis and turnover of collagen fibers. Because the JAK-STAT signaling pathway is involved in the regulation of genes encoding matrix metalloproteinases (MMPs), we examined the expression o...

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Detalhes bibliográficos
Main Authors: Bock, Oliver, Neuse, Johanne, Hussein, Kais, Brakensiek, Kai, Buesche, Guntram, Buhr, Thomas, Wiese, Birgitt, Kreipe, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780160/
https://ncbi.nlm.nih.gov/pubmed/16877349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060110
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