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The Complex of Ethidium Bromide with Genomic DNA: Structure Analysis by Polarized Raman Spectroscopy

Structural properties of the complex formed between genomic DNA and the intercalating drug ethidium bromide (EtBr) have been determined by use of a Raman microscope equipped with near-infrared laser excitation. The polarized spectra, which were obtained from oriented fibers of the EtBr:DNA complex,...

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Main Authors: Tsuboi, Masamichi, Benevides, James M., Thomas, George J.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779987/
https://ncbi.nlm.nih.gov/pubmed/17098786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.093633
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