Nonintercalative binding of ethidium bromide to nucleic acids: crystal structure of an ethidium--tRNA molecular complex.

X-ray diffraction studies at 4.5-A resolution on crystals of a complex of ethidium bromide and yeast phenylalanine tRNA reveal a nonintercalative model of binding of the ethidium within the tertiary structure. This is contrary to the expected interacalative binding to the double-helical regions.

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Liebman, M, Rubin, J, Sundaralingam, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1977
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/270714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.11.4821
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