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Binding of ethidium bromide causes dissociation of the nucleosome core particle.

The binding of ethidium bromide to chicken erythrocyte core particles results in a step-wise dissociation of the structure that involves the initial release of one copy each of histones H2A and H2B. Quantitation of the dissociated DNA reveals that a critical amount of drug is required for the dissoc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McMurray, C T, van Holde, K E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3464964/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.22.8472
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