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Ethidium Bromide as a Cooperative Effector of a DNA Structure

A salt-induced cooperative conformational transition of a synthetic DNA, poly(dG-dC), is reversed by addition of ethidium bromide. Binding of the dye at high salt concentrations is highly cooperative. Circular dichroism spectra of the complex and the kinetic data support a model for this cooperative...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Pohl, Fritz M., Jovin, Thomas M., Baehr, W., Holbrook, J. J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1972
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4509343/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.12.3805
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