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Ethidium Bromide as a Cooperative Effector of a DNA Structure

A salt-induced cooperative conformational transition of a synthetic DNA, poly(dG-dC), is reversed by addition of ethidium bromide. Binding of the dye at high salt concentrations is highly cooperative. Circular dichroism spectra of the complex and the kinetic data support a model for this cooperative...

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Detalles Bibliográficos
Main Authors: Pohl, Fritz M., Jovin, Thomas M., Baehr, W., Holbrook, J. J.
Formato: Artigo
Idioma:Inglês
Publicado: 1972
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC389877/
https://ncbi.nlm.nih.gov/pubmed/4509343
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