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Graded recruitment and inactivation of single InsP(3) receptor Ca(2)(+)-release channels: implications for quartal Ca(2)(+)release

Modulation of cytoplasmic free Ca(2)(+) concentration ([Ca(2)(+)](i)) by receptor-mediated generation of inositol 1,4,5-trisphosphate (InsP(3)) and activation of its receptor (InsP(3)R), a Ca(2)(+)-release channel in the endoplasmic reticulum, is a ubiquitous signalling mechanism. A fundamental aspe...

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Hlavní autoři: Ionescu, Lucian, Cheung, King-Ho, Vais, Horia, Mak, Don-On Daniel, White, Carl, Foskett, J Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779751/
https://ncbi.nlm.nih.gov/pubmed/16644799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.109504
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