Graded recruitment and inactivation of single InsP(3) receptor Ca(2)(+)-release channels: implications for quartal Ca(2)(+)release

Modulation of cytoplasmic free Ca(2)(+) concentration ([Ca(2)(+)](i)) by receptor-mediated generation of inositol 1,4,5-trisphosphate (InsP(3)) and activation of its receptor (InsP(3)R), a Ca(2)(+)-release channel in the endoplasmic reticulum, is a ubiquitous signalling mechanism. A fundamental aspe...

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Main Authors: Ionescu, Lucian, Cheung, King-Ho, Vais, Horia, Mak, Don-On Daniel, White, Carl, Foskett, J Kevin
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2006
主題:
Cellular
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779751/
https://ncbi.nlm.nih.gov/pubmed/16644799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.109504
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