cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic β cells and rat INS-1 cells

The Epac family of cAMP-regulated guanine nucleotide exchange factors (cAMPGEFs, also known as Epac1 and Epac2) mediate stimulatory actions of the second messenger cAMP on insulin secretion from pancreatic β cells. Because Epac2 is reported to interact in vitro with the isolated nucleotide-binding f...

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Detalhes bibliográficos
Main Authors: Kang, Guoxin, Chepurny, Oleg G, Malester, Brian, Rindler, Michael J, Rehmann, Holger, Bos, Johannes L, Schwede, Frank, Coetzee, William A, Holz, George G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779745/
https://ncbi.nlm.nih.gov/pubmed/16613879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107391
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