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Inhibition of NF-κB potentiates amyloid β-mediated neuronal apoptosis
One mechanism leading to neurodegeneration during Alzheimer’s disease (AD) is amyloid β peptide (Aβ) neurotoxicity. Aβ elicits in cultured central nervous system neurons a biphasic response: a low-dose neurotrophic response and a high-dose neurotoxic response. Previously we reported that NF-κB is ac...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The National Academy of Sciences
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17796/ https://ncbi.nlm.nih.gov/pubmed/10430956 |
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