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Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts
Statins, competitive inhibitors of hydroxymethylglutaryl-CoA reductase, have recently been shown to have a therapeutic effect in rheumatoid arthritis (RA). In RA, synovial fibroblasts in the synovial lining, are believed to be particularly important in the pathogenesis of disease because they recrui...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1779395/ https://ncbi.nlm.nih.gov/pubmed/16774691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1968 |
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