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TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory and destructive disease of the joint. The synovial lining consists of two main types of cells: synovial fibroblasts and macrophages. The macrophage-derived cytokine TNFα stimulates RA synovial fibroblasts to proliferate and produce gr...

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Detalhes bibliográficos
Main Authors: Connor, Alison M, Mahomed, Nizar, Gandhi, Rajiv, Keystone, Edward C, Berger, Stuart A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446430/
https://ncbi.nlm.nih.gov/pubmed/22417670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3778
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