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Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts

Synovial hyperplasia in rheumatoid arthritis (RA) has been associated with apoptosis deficiency of RA fibroblast-like synoviocytes (FLSs). Celecoxib is a non-steroidal anti-inflammatory drug that has been demonstrated to induce apoptosis in some cellular systems. We have therefore examined the dose-...

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Detalhes bibliográficos
Main Authors: Audo, Rachel, Deschamps, Véronique, Hahne, Michael, Combe, Bernard, Morel, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246250/
https://ncbi.nlm.nih.gov/pubmed/18076767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2342
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