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Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes

Spontaneous autoimmune diabetes in nonobese diabetic (NOD) mice is the result of a CD4(+) and CD8(+) T cell-dependent autoimmune process directed against the pancreatic beta cells. CD8(+) T cells play a critical role in the initiation and progression of diabetes, but the specificity and diversity of...

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書誌詳細
主要な著者: Anderson, Brad, Park, Bjung-Ju, Verdaguer, Joan, Amrani, Abdelaziz, Santamaria, Pere
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC17778/
https://ncbi.nlm.nih.gov/pubmed/10430939
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