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The role of MHC class II molecules in susceptibility to type I diabetes: Identification of peptide epitopes and characterization of the T cell repertoire

Susceptibility to type I diabetes is linked to class II MHC alleles in both mouse and man. However, the molecular mechanisms by which MHC molecules mediate disease susceptibility are unknown. To analyze how I-A alleles predispose to, or prevent, the development of type I diabetes, we have chosen, as...

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Main Authors: Chao, Cheng-Chi, Sytwu, Huey-Kang, Chen, Emily Lichuan, Toma, Jon, McDevitt, Hugh O.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17775/
https://ncbi.nlm.nih.gov/pubmed/10430937
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