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Dominant negative rat DNA polymerase beta mutants interfere with base excision repair in Saccharomyces cerevisiae.

DNA polymerase beta is one of the smallest known eukaryotic DNA polymerases. This polymerase has been very well characterized in vitro, but its functional role in vivo has yet to be determined. Using a novel competition assay in Escherichia coli, we isolated two DNA polymerase beta dominant negative...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Clairmont, C A, Sweasy, J B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8550496/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.3.656-661.1996
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