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Biological actions in vivo and in vitro of two γ-aminobutyric acid (GABA) analogues: β-chloro GABA and β-phenyl GABA

1 The synthesis of two analogues of γ-aminobutyric acid (GABA), β-chloro GABA and β-phenyl GABA is described. 2 The activity of brain GABA aminotransferase was inhibited by β-chloro GABA (5.7 × 10(-5) M) and β-phenyl GABA (4.6 × 10(-3) M) in a competitive manner with GABA. 3 β-Chloro GABA exhibited...

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Detalles Bibliográficos
Autores principales: Buu, N.T., Van Gelder, N.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1974
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1777036/
https://ncbi.nlm.nih.gov/pubmed/4156485
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