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Absorption, metabolism and distribution of [(14)C]-O-methyldopa and [(14)C]-L-dopa after oral administration to rats

1 The absorption, tissue distribution, and metabolism of [(14)C]-O-methyldopa were compared with those of [(14)C]-L-DOPA after oral administration to rats. 2 Total radioactivity in the plasma and brain of rats treated with [(14)C]-O-methyldopa was significantly higher (2 fold and 30-50 fold, respect...

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Bibliographic Details
Main Author: Rivera-Calimlim, Leonor
Format: Artigo
Language:Inglês
Published: 1974
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776645/
https://ncbi.nlm.nih.gov/pubmed/4425764
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