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Absorption, distribution, metabolism, and excretion of [(14)C]‐dasotraline in humans

Dasotraline is a dopamine and norepinephrine reuptake inhibitor, and the early clinical trials show a slow absorption and long elimination half‐life. To investigate the absorption, distribution, metabolism, and excretion of dasotraline in humans, a single dose of [(14)C]‐dasotraline was administered...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacol Res Perspect
Prif Awduron: Chen, Yu‐Luan, Skende, Estela, Lin, Jing, Yi, Yijun, Wang, Peter L., Wills, Sarah, Wilkinson, H. Scott, Koblan, Kenneth S., Hopkins, Seth C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461651/
https://ncbi.nlm.nih.gov/pubmed/28596833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.281
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