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A silencer element identified in Drosophila is required for imprinting of H19 reporter transgenes in mice

The H19 gene is subject to genomic imprinting because it is methylated and repressed after paternal inheritance and is unmethylated and expressed after maternal inheritance. We recently identified a 1.1-kb control element in the upstream region of the H19 gene that functions as a cis-acting silencer...

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Main Authors: Brenton, J. D., Drewell, R. A., Viville, S., Hilton, K. J., Barton, S. C., Ainscough, J. F-X., Surani, M. A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 1999
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC17764/
https://ncbi.nlm.nih.gov/pubmed/10430927
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