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Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic Drosophila
The imprinting control region (ICR) upstream of H19 is the key regulatory element conferring monoallelic expression on H19 and Igf2 (insulin-like growth factor 2). Epigenetic marks in the ICR regulate its interaction with the chromatin protein CCCTC-binding factor and with other control factors to c...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2247386/ https://ncbi.nlm.nih.gov/pubmed/17948025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401094 |
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