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Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic Drosophila

The imprinting control region (ICR) upstream of H19 is the key regulatory element conferring monoallelic expression on H19 and Igf2 (insulin-like growth factor 2). Epigenetic marks in the ICR regulate its interaction with the chromatin protein CCCTC-binding factor and with other control factors to c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schoenfelder, Stefan, Smits, Guillaume, Fraser, Peter, Reik, Wolf, Paro, Renato
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247386/
https://ncbi.nlm.nih.gov/pubmed/17948025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401094
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