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Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic Drosophila
The imprinting control region (ICR) upstream of H19 is the key regulatory element conferring monoallelic expression on H19 and Igf2 (insulin-like growth factor 2). Epigenetic marks in the ICR regulate its interaction with the chromatin protein CCCTC-binding factor and with other control factors to c...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2247386/ https://ncbi.nlm.nih.gov/pubmed/17948025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401094 |
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