Promoter, enhancer and silencer elements regulate rearrangement of an immunoglobulin transgene.

The chicken Ig lambda light chain locus is composed of a single V gene closely linked (1.8 kb) to a single J-C unit in its natural configuration. In mice transgenic for this locus, the transgene becomes rearranged in B cells and to a much lesser extent in T cells. Modifications were introduced in th...

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Main Authors: Lauster, R, Reynaud, C A, Mårtensson, I L, Peter, A, Bucchini, D, Jami, J, Weill, J C
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC413898/
https://ncbi.nlm.nih.gov/pubmed/8223471
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