Effects of a minor isoleucyl tRNA on heterologous protein translation in Escherichia coli.

In Escherichia coli, the isoleucine codon AUA occurs at a frequency of about 0.4% and is the fifth rarest codon in E. coli mRNA. Since there is a correlation between the frequency of codon usage and the level of its cognate tRNA, translational problems might be expected when the mRNA contains high l...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Del Tito, B J, Ward, J M, Hodgson, J, Gershater, C J, Edwards, H, Wysocki, L A, Watson, F A, Sathe, G, Kane, J F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8522513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.24.7086-7091.1995
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