Effects of a minor isoleucyl tRNA on heterologous protein translation in Escherichia coli.

In Escherichia coli, the isoleucine codon AUA occurs at a frequency of about 0.4% and is the fifth rarest codon in E. coli mRNA. Since there is a correlation between the frequency of codon usage and the level of its cognate tRNA, translational problems might be expected when the mRNA contains high l...

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Detalhes bibliográficos
Main Authors: Del Tito, B J, Ward, J M, Hodgson, J, Gershater, C J, Edwards, H, Wysocki, L A, Watson, F A, Sathe, G, Kane, J F
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC177585/
https://ncbi.nlm.nih.gov/pubmed/8522513
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