The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma

Background: Accumulation of molecular alterations, including mutations in Kirsten-ras (K-ras), p53, and adenomatous polyposis coli (APC), contribute to colorectal carcinogenesis. Our group has previously characterised a panel of sporadic colorectal adenocarcinomas for mutations in these three genes...

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Bibliografiske detaljer
Main Authors: Conlin, A, Smith, G, Carey, F A, Wolf, C R, Steele, R J C
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2005 by Gut 2005
Fag:
Colorectal Cancer
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774675/
https://ncbi.nlm.nih.gov/pubmed/15843421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.066514
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