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Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer
Colorectal cancer is one of the most significant causes of cancer death. A genetic model for colorectal cancer has been proposed in which the sequential accumulation of mutations in specific genes, including adenomatous polyposis coli (APC), Kirsten-ras (K-ras), and p53, drives the transition from h...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123158/ https://ncbi.nlm.nih.gov/pubmed/12093899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122612899 |
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