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Mutations of Ki-ras and p53 genes in colorectal cancer and their prognostic significance.

The series of genetic changes leading to malignancy in colorectal cancer is well reported. This includes mutational activation of the proto-oncogene Ki-ras and mutation/deletion of the p53 tumour suppressor gene. The frequency of these mutations was investigated in a panel of 52 colorectal cancer pa...

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Autors principals: Morrin, M, Kelly, M, Barrett, N, Delaney, P
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1375626/
https://ncbi.nlm.nih.gov/pubmed/7828987
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