Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa

Background: Enteropathy in coeliac disease (CD) is sustained by a gliadin specific Th1 response. Interleukin (IL)-10 can downregulate Th1 immune responses. Aim: We investigated the ability of recombinant human (rh) IL-10 to suppress gliadin induced Th1 response. Patients and methods: IL-10 RNA trans...

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Main Authors: Salvati, V M, Mazzarella, G, Gianfrani, C, Levings, M K, Stefanile, R, De Giulio, B, Iaquinto, G, Giardullo, N, Auricchio, S, Roncarolo, M G, Troncone, R
Formato: Artigo
Idioma:Inglês
Publicado: Copyright 2005 by Gut 2005
Assuntos:
Coeliac Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774366/
https://ncbi.nlm.nih.gov/pubmed/15591503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.023150
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