Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat

Background: Taurolithocholate induced cholestasis is a well established model of drug induced cholestasis with potential clinical relevance. This compound impairs bile salt secretion by an as yet unclear mechanism. Aims: To evaluate which step/s of the hepatocellular bile salt transport are impaired...

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Main Authors: Crocenzi, F A, Mottino, A D, Sánchez Pozzi, E J, Pellegrino, J M, Rodríguez Garay, E A, Milkiewicz, P, Vore, M, Coleman, R, Roma, M G
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2003
Fag:
Biliary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773741/
https://ncbi.nlm.nih.gov/pubmed/12865277
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