Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma

Backgrounds: The Raf/MEK/ERK (mitogen activated protein kinase—MAPK) signal transduction cascade is an important mediator of a number of cellular fates, including growth, proliferation, and survival. The BRAF gene, one of the human isoforms of RAF, is activated by oncogenic Ras, leading to cooperati...

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Détails bibliographiques
Auteurs principaux: Tannapfel, A, Sommerer, F, Benicke, M, Katalinic, A, Uhlmann, D, Witzigmann, H, Hauss, J, Wittekind, C
Format: Artigo
Langue:Inglês
Publié: Copyright 2003 by Gut 2003
Sujets:
Liver
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773624/
https://ncbi.nlm.nih.gov/pubmed/12692057
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