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Frequency of p16(INK4A) alterations and k-ras mutations in intrahepatic cholangiocarcinoma of the liver
BACKGROUND—Inactivation of the tumour suppressor gene p16 (CDKN2/MTS-1/INK4A) and K-ras mutations are among the most frequent genetic alterations in human malignancies. AIMS—To investigate the tumour suppressor gene p16 and its possible association with K-ras mutations in intrahepatic cholangiocarci...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1728101/ https://ncbi.nlm.nih.gov/pubmed/11034592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.5.721 |
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