Increased mucosal tumour necrosis factor α production in Crohn’s disease can be downregulated ex vivo by probiotic bacteria

Background and aims: Tumour necrosis factor α (TNF-α) plays a key role in the pathogenesis of intestinal inflammation in Crohn’s disease. The effect of bacteria on TNF-α release by intestinal mucosa was investigated. Methods: Ileal specimens were obtained at surgery from 10 patients with Crohn’s dis...

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Autors principals: Borruel, N, Carol, M, Casellas, F, Antolín, M, de Lara, F, Espín, E, Naval, J, Guarner, F, Malagelada, J R
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2002 by Gut 2002
Matèries:
Inflammatory Bowel Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773447/
https://ncbi.nlm.nih.gov/pubmed/12377803
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