Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor α antibody treatment

Background and aims: Barrier dysfunction is an important feature contributing to inflammation and diarrhoea in Crohn’s disease (CD). Recently, tumour necrosis factor α (TNF-α) antibodies were recognised as effective in steroid refractory CD. The aim of this study was to characterise the effects of t...

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Hlavní autoři: Zeissig, S, Bojarski, C, Buergel, N, Mankertz, J, Zeitz, M, Fromm, M, Schulzke, J D
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2004 by Gut 2004
Témata:
Inflammatory Bowel Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774168/
https://ncbi.nlm.nih.gov/pubmed/15306588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.036632
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