Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis

Background: Crohn's disease is characterised by a chronic relapsing inflammation of the bowel in which proinflammatory cytokines play an important perpetuating role. Mitogen activated protein kinase p38 (p38 MAPK) has been established as a major regulator of the inflammatory response, especiall...

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Bibliographic Details
Main Authors: ten Hove, T, van den Blink, B, Pronk, I, Drillenburg, P, Peppelenbosch, M P, van Deventer, S J H
Format: Artigo
Language:Inglês
Published: Copyright 2002 by Gut 2002
Subjects:
Inflammation and Inflammatory Bowel Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773163/
https://ncbi.nlm.nih.gov/pubmed/11889071
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