Apoptosis and proliferation of acinar and islet cells in chronic pancreatitis: evidence for differential cell loss mediating preservation of islet function

Background: Chronic pancreatitis is characterised clinically by early exocrine insufficiency, with diabetes mellitus occurring as a late phenomenon. This is mirrored pathologically by extensive acinar cell destruction and islet preservation. The mechanisms underlying this differential rate of cellul...

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Main Authors: Bateman, A C, Turner, S M, Thomas, K S A, McCrudden, P R, Fine, D R, Johnson, P A, Johnson, C D, Iredale, J P
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2002 by Gut 2002
Fag:
Pancreatic Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773161/
https://ncbi.nlm.nih.gov/pubmed/11889077
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