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β Cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice
Type 1 diabetes (T1D) is caused by the destruction of insulin-producing islet β cells. CD8 T cells are prevalent in the islets of T1D patients and are the major effectors of β cell destruction in nonobese diabetic (NOD) mice. In addition to their critical involvement in the late stages of diabetes,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1773057/ https://ncbi.nlm.nih.gov/pubmed/17229843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610057104 |
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