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β Cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice

Type 1 diabetes (T1D) is caused by the destruction of insulin-producing islet β cells. CD8 T cells are prevalent in the islets of T1D patients and are the major effectors of β cell destruction in nonobese diabetic (NOD) mice. In addition to their critical involvement in the late stages of diabetes,...

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Detalhes bibliográficos
Main Authors: de Jersey, James, Snelgrove, Sarah L., Palmer, Stephanie E., Teteris, Simon A., Mullbacher, Arno, Miller, Jacques F. A. P., Slattery, Robyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773057/
https://ncbi.nlm.nih.gov/pubmed/17229843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610057104
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