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Mutagenesis of the IS1 transposase: importance of a His-Arg-Tyr triad for activity.

Inspection of the primary sequence of the IS1 transposase suggested that it carries residues which are characteristic of the active site of integrases of the bacteriophage lambda family (Int). In particular, these include a highly conserved triad: His-Arg-Tyr. The properties of mutants made at each...

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Autors principals: Serre, M C, Turlan, C, Bortolin, M, Chandler, M
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC177286/
https://ncbi.nlm.nih.gov/pubmed/7665486
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