Substrate requirements for ErmC' methyltransferase activity.

ErmC' is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalyzing the methylation of 23S rRNA at a specific adenine residue (A-2085 in Bacillus subtilis; A-2058 in Escherichia coli). The gene for ErmC' was cloned and expres...

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Bibliografiske detaljer
Main Authors: Zhong, P, Pratt, S D, Edalji, R P, Walter, K A, Holzman, T F, Shivakumar, A G, Katz, L
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC177180/
https://ncbi.nlm.nih.gov/pubmed/7543473
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