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Substrate requirements for ErmC' methyltransferase activity.

ErmC' is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalyzing the methylation of 23S rRNA at a specific adenine residue (A-2085 in Bacillus subtilis; A-2058 in Escherichia coli). The gene for ErmC' was cloned and expressed to a h...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Zhong, P, Pratt, S D, Edalji, R P, Walter, K A, Holzman, T F, Shivakumar, A G, Katz, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177180/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7543473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.15.4327-4332.1995
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